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Industry News


                                                                                                                                 such as paraplegia or amyotrophic lateral              3D-printed Medication for Toxoplasmosis
                                                                                                                                 sclerosis, where muscle paralysis limits the use of
                                                                                                                                                                                        Toxoplasmosis is a parasitic infection that
                                                                                                                                 limbs.
                                                                                                                                                                                        affects over a billion people across the world.
                                                                                                                                 Neuroprostheses, which use BCIs to bridge              It is particularly harmful to pregnant women,
                                                                                                                                 damaged nerve pathways and translate brain             whose children can suffer blindness, deafness,
                                                                                                                                 signals into movements, are not new, but the           seizures and mental health issues. Tablets
                                                                                                                                 limited fine motor capabilities of current hand        exist, but these adult drugs are expensive and
                                                                                                                                 prostheses has hindered their practical use.           have to be altered by pharmacists to make
                                                                                                                                                                                        them suitable for children, with a resultant
                                                                                                                                 In this experiment two rhesus monkeys, which
                                                                                                                                                                                        variation in quality, strength and stability.
                                                                                                                                 share similarities with humans in nervous system
                                                                                                                                 development and fine motor skills, were trained        Now, researchers at Texas A and M University
                                                                                                                                 to move a virtual avatar hand displayed on a           are applying 3D-printing to create a form of the
                                                                                                                                 screen using their own hand movements. A               drug that is specifically tailored for children with
                                                                                                                                 data glove, equipped with magnetic sensors,            the help of a $3.1 million grant from the National
                                                                                                                                 recorded the results. The monkeys then learned         Institutes of Health.
                                                                                                                                 to control the virtual hand by thought alone, with
          MEDICAL FOCUS                                                                                                          neuronal activity in the cortical brain areas that     The type of 3D-printing being used is that of
                                                                                                                                                                                        biofabrication, which allows for precise, patient-
                                                                                                                                 control hand movements being monitored.
                                                                                                                                                                                        specific adjustments to be made to drugs,
                                                                                                                                 In order to improve the algorithm that converts        medical models and implants. Different forms
                                                                                                                                 neural data into movement the BCI protocol was         of the process are used to address different
                                                                                                                                 adjusted so as to prioritise not just the end point    medical applications. In this case Selective Laser
                                                                                                                                 of a movement, but also its execution path.            Sintering is used to produce dissolvable tablets
                                                                                                                                                                                        by adjusting laser and material parameters
                                                                                                                                 Comparison between the movements of the
                                                                                                                                                                                        to create dose consistency and stability. Other
                                                                                                                                 virtual hand and the real hand, as recorded
                                                                                                                                                                                        methods, however, such as extrusion-based
          Using AI to improve Diagnosis                         will analyse large sets of referral data with the                previously, showed a high degree of precision,
                                                                                                                                                                                        printing and inkjet printing, can also be applied
          of Inflammatory Arthritis                             machine learning system, RMD-Health, serving                     validating the effectiveness of the new protocol.
                                                                                                                                                                                        for layering ingredients to allow for controlled-
                                                                to identify patterns that may not be initially
          Researchers at the Henley Business School                                                                              Andres Agudelo-Toro, First Author of the study         release tablets that have to be administered
                                                                obvious to clinicians.
          have been awarded £600,000 from UK                                                                                     at the Neurobiology Laboratory of the German           over time without re-dosing.
          Research and Innovation to pioneer a                  The project is set to last 18 months and will                    Primate Centre, explains:
                                                                                                                                                                                        The ultimate objective is to be able to supply the
          project that will use machine learning                involve collaboration with the University of Oxford
                                                                                                                                 “ How well a prosthesis works depends primarily        appropriate 3D-printing machines to hospitals
          to revolutionise the early detection of               and the Royal Berkshire NHS Foundation who will
                                                                                                                                 on the neural data read by the computer                so that medical facilities will be available to
          inflammatory arthritis, a condition which,            be testing the AI system in real-world clinical
                                                                                                                                 interface that controls it. Previous studies on        produce personalised doses on demand.
          if diagnosed late, can lead to long-term loss of      settings.
                                                                                                                                 arm and hand movements have focused on the             Selective Laser Sintering has enabled control of
          mobility. Around 400,000 people in the UK are
                                                                Reference: Miles, S., ‘AI aims to transform early Arthritis Detection and   signals that control the velocity of a grasping   factors such as hardness, dissolution rate and
          estimated to be living with it.                       Treatment’, Electronic Specifier, 18th. October.
                                                                                                                                 movement. We wanted to find out whether                speed of absorption into the body. Longer term
          This ‘power beaming’  is seen as being ‘a The                                                                          neural signals representing hand postures might        objectives include application to, for example,
          project will use artificial intelligence to assist    Breakthrough in neural Control                                   be better suited to control neuroprostheses.           limb regeneration.
          doctors to identify the signs of this crippling       of Prosthetic Hands                                              Deviating from the classic protocol, we adapted        Reference: Miles, S., ‘3D-printing Medicine for Children’, Electronic
          condition before it becomes far worse. The AI                                                                                                                                 Specifier, 29th. October.
                                                                Researchers at the German Primate Centre                         the algorithm so that not only the destination of
                                                                - Leibnitz Institute for Primate Research in                     a movement is important, but also how you get
                                                                Gottingen have developed a new protocol                          there, that is the path of execution. This ultimately
                                                                for brain-computer interfaces (BCI) that has                     led to the most accurate results.”
              Visit our                                         achieved a major advance in prosthetic hand                      Hansjorg Scherberger, Senior Author and Head of
                                                                control.                                                         the Neurobiology Laboratory, adds:
             website!                                           When tested on rhesus monkeys the new
                                                                                                                                 “ In our study we were able to show that the
                                                                method demonstrated precise manipulation of
             Why not head down to our                                                                                            signals that control the posture of a hand
                                                                prosthetic hands using neural signals alone.
                                                                                                                                 are particularly important for controlling a
               website and read more
                                                                Previously BCI research has focused on signals                   neuroprosthesis. These results can now be used
              news in our blog section?
                                                                that govern speed of movement, but this latest                   to improve the functionality of future brain-
                  Updated daily with                            research has found that the neural signal                        computer interfaces and thus also to improve
                                                                responsible for different hand postures play                     the fine motor skills of neural prostheses.”
                 hand-picked articles
                                                                a more crucial role in controlling prosthetic                    Reference: West, P., ‘Researchers achieve Breakthrough in neural
                from around the web...
                                                                devices. This is anticipated to enhance the fine                 Control of Prosthetic Hands’, Electronic Specifier, 21st. October.
                                                                control of neural prostheses, potentially restoring
            institutionofelectronics.ac.uk
                                                                some or all mobility to individuals with conditions

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